Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies

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Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies

Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections in infants and the elderly, and yet there remains no effective treatment or vaccine. The surface of the virion is decorated with the fusion glycoprotein (RSV F) and the attachment glycoprotein (RSV G), which binds to CX3CR1 on human airway epithelial cells to mediate viral attachment and subsequent i...

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ژورنال

عنوان ژورنال: PLOS Pathogens

سال: 2018

ISSN: 1553-7374

DOI: 10.1371/journal.ppat.1006935